Ovarian dysfunction: estrogen excess

DOID EFO MESH PheWeb

E4_ODESTRO

hyperestrogenism: ['Abnormally high level of estrogen. [ NICHD NCI ]']

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule

Sex only females

180574

Check conditions None

180574

Filter registries

Hospital Discharge: ICD-10 E28.0#

Hospital discharge: ICD-9 2560

Hospital discharge: ICD-8 2560

Cause of death: ICD-10 E28.0#

Cause of death: ICD-9 2560

Cause of death: ICD-8 2560

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

E4_ODESTRO

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 E28

Name in latin Hypersecretio oestrogenorum

Similar endpoints

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List of similar endpoints to Ovarian dysfunction: estrogen excess based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	31	31	-
Unadjusted prevalence (%)	0.01	0.02	-
Mean age at first event (years)	33.36	33.36	-

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_ODESTRO – Ovarian dysfunction: estrogen excess
GWS hits:

Survival analyses between endpoints

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Plot

before Ovarian dysfunction: estrogen excess
after Ovarian dysfunction: estrogen excess

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Table

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Drugs most likely to be purchased after Ovarian dysfunction: estrogen excess

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