Hypothyroidism due to medicaments and other exogenous substances

DOID EFO MESH SNOMED PheWeb

E4_HYTHYSUBS

hypothyroidism: Abnormally low levels of thyroid hormone.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E03.2#

Hospital discharge: ICD-9 2443

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 E03.2#

Cause of death: ICD-9 2443

Cause of death: ICD-8 $!$

186

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

186

Check minimum number of events None

186

Include endpoints None

186

E4_HYTHYSUBS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 E03

Name in latin Hypothyreosis ex medicamentis sive aliis substantiis externis

Similar endpoints

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List of similar endpoints to Hypothyroidism due to medicaments and other exogenous substances based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	182	128	54
Unadjusted prevalence (%)	0.06	0.07	0.04
Mean age at first event (years)	56.95	55.22	61.05

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_HYTHYSUBS – Hypothyroidism due to medicaments and other exogenous substances
GWS hits: 0

Survival analyses between endpoints

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Plot

before Hypothyroidism due to medicaments and other exogenous substances
after Hypothyroidism due to medicaments and other exogenous substances

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Table

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Drugs most likely to be purchased after Hypothyroidism due to medicaments and other exogenous substances

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