Graves disease, strict definition

E4_GRAVES_STRICT

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions

GRAVES_COND
and not AMIODARONE

9305

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

2386

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E4_GRAVES_STRICT

Extra metadata

First used in FinnGen datafreeze DF7

Summary Statistics

Key figures

All Female Male
Number of individuals 2311 1963 348
Unadjusted prevalence (%) 0.75 1.13 0.26
Mean age at first event (years) 49.49 48.97 52.44

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.87 [0.82, 4.26] 1.4e-1 54
15 years 0.01 1.29 [0.65, 2.57] 4.6e-1 26
5 years 0.00 2.21 [1.18, 4.16] 1.4e-2 15
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_GRAVES_STRICT – Graves disease, strict definition
GWS hits:

Survival analyses between endpoints

Plot

before Graves disease, strict definition
after Graves disease, strict definition

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Drugs most likely to be purchased after Graves disease, strict definition