Carbimazole or st.post thyredectomy, condition for graves disease

PheWeb

GRAVES_COND

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Operations: NOMESCO codes ^BA

Medicine purchases: ATC H03BB01

10819

Check pre-conditions, main-only, mode, ICD version None

9491

Check minimum number of events

Min. number of events 3

9491

Include endpoints None

9491

GRAVES_COND

Extra metadata

First used in FinnGen datafreeze DF7

Similar endpoints

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List of similar endpoints to Carbimazole or st.post thyredectomy, condition for graves disease based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Graves disease, strict definition

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	9186	7343	1843
Unadjusted prevalence (%)	2.98	4.23	1.36
Mean age at first event (years)	54.24	53.06	58.93

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.82 [1.40, 2.36]	8.3e-6	371
15 years	0.01	1.08 [0.84, 1.40]	5.5e-1	173
5 years	0.00	1.93 [1.46, 2.54]	3.3e-6	106
1 year	0.00	5.79 [4.20, 7.99]	8.8e-27	60

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: GRAVES_COND – Carbimazole or st.post thyredectomy, condition for graves disease
GWS hits:

Survival analyses between endpoints

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Plot

before Carbimazole or st.post thyredectomy, condition for graves disease
after Carbimazole or st.post thyredectomy, condition for graves disease

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Table

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Drugs most likely to be purchased after Carbimazole or st.post thyredectomy, condition for graves disease

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