Nontoxic single thyroid nodule

E4_GOITRENOD

nodular goiter: Goiter characterized by discrete tissue mass(es) that may or may not produce thyroid hormones.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 E04.1
Hospital discharge: ICD-9 2410|2462
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 E04.1
Cause of death: ICD-9 2410|2462
Cause of death: ICD-8 $!$

1754

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1692

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Check minimum number of events None

1692

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Include endpoints None

1692

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E4_GOITRENOD

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E04
Name in latin Struma atoxica uninodularis

Summary Statistics

Key figures

All Female Male
Number of individuals 1634 1327 307
Unadjusted prevalence (%) 0.53 0.76 0.23
Mean age at first event (years) 50.81 49.37 57.04

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.77 [0.42, 1.40] 3.9e-1 63
15 years 0.00 0.51 [0.27, 0.98] 4.3e-2 29
5 years 0.00 0.93 [0.43, 2.01] 8.5e-1 11
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_GOITRENOD – Nontoxic single thyroid nodule
GWS hits: 1

Survival analyses between endpoints

Plot

before Nontoxic single thyroid nodule
after Nontoxic single thyroid nodule

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Nontoxic single thyroid nodule