Nontoxic diffuse goitre

E4_GOITREDIFF

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 E04.0
Hospital discharge: ICD-9 2400
Hospital discharge: ICD-8 240
Cause of death: ICD-10 E04.0
Cause of death: ICD-9 2400
Cause of death: ICD-8 240

785

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

709

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Check minimum number of events None

709

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Include endpoints None

709

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E4_GOITREDIFF

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E04
Name in latin Struma atoxica diffusa

Summary Statistics

Key figures

All Female Male
Number of individuals 685 582 103
Unadjusted prevalence (%) 0.22 0.34 0.08
Mean age at first event (years) 50.64 49.88 54.89

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 1.04 [0.56, 1.91] 9.0e-1 46
15 years 0.00 0.69 [0.37, 1.27] 2.3e-1 20
5 years 0.00 1.45 [0.73, 2.90] 2.9e-1 11
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_GOITREDIFF – Nontoxic diffuse goitre
GWS hits: 3

Survival analyses between endpoints

Plot

before Nontoxic diffuse goitre
after Nontoxic diffuse goitre

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Drugs most likely to be purchased after Nontoxic diffuse goitre