Disorders of calcium metabolism

E4_CA_MET

calcium metabolic disease: Disorders in the processing of calcium in the body: its absorption, transport, storage, and utilization.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E83.50, E83.50+F02.89, E83.50+N16.3, E83.51, E83.58, E83.59

Hospital discharge: ICD-9 2754

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 E83.50, E83.50+F02.89, E83.50+N16.3, E83.51, E83.58, E83.59

Cause of death: ICD-9 2754

Cause of death: ICD-8 $!$

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

1210

E4_CA_MET

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Disorders of calcium metabolism based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1168	717	451
Unadjusted prevalence (%)	0.38	0.41	0.33
Mean age at first event (years)	60.01	59.05	61.55

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	3.75 [1.62, 8.66]	2.0e-3	188
15 years	0.01	1.06 [0.51, 2.18]	8.8e-1	35
5 years	0.01	4.63 [2.74, 7.84]	1.1e-8	49
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_CA_MET – Disorders of calcium metabolism
GWS hits: 0

Survival analyses between endpoints

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Plot

before Disorders of calcium metabolism
after Disorders of calcium metabolism

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Table

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Drugs most likely to be purchased after Disorders of calcium metabolism

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