Exclude non-diabetic causes for injection of anti-VEGF-antibody or corticosteroid or any drug into vitreous body

PheWeb

DM_EYE_OPER_FOR_NON_DIAB_EXCLUSION

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions

DIABETES_FG

55191

Filter registries

Hospital Discharge: ICD-10 H34.8, H35.31

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 H34.8, H35.31

Cause of death: ICD-9 $!$

Cause of death: ICD-8 $!$

1654

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1654

Check minimum number of events None

1654

Include endpoints None

1654

DM_EYE_OPER_FOR_NON_DIAB_EXCLUSION

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Exclude non-diabetic causes for injection of anti-VEGF-antibody or corticosteroid or any drug into vitreous body based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Retinal vein occlusion (central or branch)

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1606	771	835
Unadjusted prevalence (%)	0.52	0.44	0.62
Mean age at first event (years)	71.40	71.98	70.88

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	3.51 [2.47, 5.00]	3.3e-12	290
15 years	0.01	1.75 [1.25, 2.46]	1.2e-3	133
5 years	0.00	3.16 [2.24, 4.46]	6.2e-11	120
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: DM_EYE_OPER_FOR_NON_DIAB_EXCLUSION – Exclude non-diabetic causes for injection of anti-VEGF-antibody or corticosteroid or any drug into vitreous body
GWS hits:

Survival analyses between endpoints

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Plot

before Exclude non-diabetic causes for injection of anti-VEGF-antibody or corticosteroid or any drug into vitreous body
after Exclude non-diabetic causes for injection of anti-VEGF-antibody or corticosteroid or any drug into vitreous body

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Table

Loading survival analyses table

Drugs most likely to be purchased after Exclude non-diabetic causes for injection of anti-VEGF-antibody or corticosteroid or any drug into vitreous body

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