Retinal vein occlusion (central or branch)

DM_RET_VEIN_OCCLU

retinal vein occlusion: Blockage of the RETINAL VEIN. Those at high risk for this condition include patients with HYPERTENSION; DIABETES MELLITUS; ATHEROSCLEROSIS; and other CARDIOVASCULAR DISEASES.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions

DIABETES_FG

55191

Filter registries

Hospital Discharge: ICD-10 H34.8

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 H34.8

Cause of death: ICD-9 $!$

Cause of death: ICD-8 $!$

591

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

591

Check minimum number of events None

591

Include endpoints None

591

DM_RET_VEIN_OCCLU

Extra metadata

First used in FinnGen datafreeze DF2

Parent code in ICD-10 H34

Name in latin Aliae occlusiones vasculares retinae specificatae

Similar endpoints

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List of similar endpoints to Retinal vein occlusion (central or branch) based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

All

Female

Male

Number of individuals

572

258

314

Unadjusted prevalence (%)

0.19

0.15

0.23

Mean age at first event (years)

66.79

66.03

67.41

?

Follow-up

Amount of time to look for the endpoint since entering the study. This is either either 1, 5, 15 years or the full study time from 1998 to 2019.

Absolute risk

Estimates the probability of dying from the current endpoint. Check the Documentation page for Mortality: absolute risk to get more details.

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Measures how much the risk of dying increases (HR > 1) or decreases (HR < 1).

Number of individuals (N)

Number of individuals having the current endpoint and died during the follow-up time.
Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.26 [1.06, 4.81]	3.5e-2	92
15 years	0.01	1.12 [0.54, 2.35]	7.6e-1	43
5 years	0.00	3.33 [1.88, 5.89]	3.7e-5	37
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: DM_RET_VEIN_OCCLU – Retinal vein occlusion (central or branch)
GWS hits: 1

Survival analyses between endpoints

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Plot

before Retinal vein occlusion (central or branch)
after Retinal vein occlusion (central or branch)

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Retinal vein occlusion (central or branch)

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