Severe non-proliferative background diabetic retinopathy

DM_BCKGRND_RETINA_NONPROLIF

proliferative diabetic retinopathy: Later stage of diabetic retinopathy, characterized by neovascularisation of the retina

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 H36.02*

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 H36.02*

Cause of death: ICD-9 $!$

Cause of death: ICD-8 $!$

696

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

696

Check minimum number of events None

696

Include endpoints None

696

DM_BCKGRND_RETINA_NONPROLIF

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Severe non-proliferative background diabetic retinopathy based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Severe diabetic background retinopathy

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	672	277	395
Unadjusted prevalence (%)	0.22	0.16	0.29
Mean age at first event (years)	46.65	44.49	48.17

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.09	7.33 [4.26, 12.63]	6.8e-13	74
15 years	0.02	3.59 [2.08, 6.20]	4.5e-6	34
5 years	0.01	7.85 [4.61, 13.35]	3.0e-14	30
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: DM_BCKGRND_RETINA_NONPROLIF – Severe non-proliferative background diabetic retinopathy
GWS hits: 2

Survival analyses between endpoints

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Plot

before Severe non-proliferative background diabetic retinopathy
after Severe non-proliferative background diabetic retinopathy

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Severe non-proliferative background diabetic retinopathy

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