Endpoint definition
↥321302 individuals
Apply sex-specific rule None
321302
Check conditions None
321302
Check pre-conditions, main-only, mode, ICD version
-
Check minimum number of events None
-
Extra metadata
D3_CVID
obsolete_common variable immunodeficiency: ['A hypogammaglobulinemia that is results in insufficient production of antibodies needed to respond to exposure of pathogens and is characterized by low Ig levels with phenotypically normal B cells that can proliferate but do not develop into Ig-producing cells. Patients with common variable immunodeficiency have marked reduction in serum levels of both immunoglobulin G (IgG) and immunoglobulin A (IgA); about half of these patients also have reduced immunoglobulin M (IgM).', 'A primary immunodeficiency characterized by low levels or absence of all the immunoglobulin classes and lack of B-lymphocytes or plasma cells. It results in recurrent bacterial infections. Complications include autoimmune phenomena and cancer development.', 'Heterogeneous group of immunodeficiency syndromes characterized by hypogammaglobulinemia of most isotypes, variable B-cell defects, and the presence of recurrent bacterial infections.']
321302 individuals
Apply sex-specific rule None
321302
Check conditions None
321302
Check pre-conditions, main-only, mode, ICD version
-
Check minimum number of events None
-
Extra metadata
List of similar endpoints to Common variable immunodeficiency based on the number of shared cases.
Broader endpoints:
Narrower endpoints:
All | Female | Male | |
---|---|---|---|
Number of individuals | 132 | 82 | 50 |
Unadjusted prevalence (%) | 0.04 | 0.05 | 0.04 |
Mean age at first event (years) | 48.98 | 49.65 | 47.89 |
Follow-up | Absolute risk | HR [95% CI] | p | N |
---|---|---|---|---|
1998–2019 | - | - | - | - |
15 years | - | - | - | - |
5 years | - | - | - | - |
1 year | - | - | - | - |
Index endpoint: D3_CVID – Common variable immunodeficiency
GWS hits:
before Common variable immunodeficiency
after Common variable immunodeficiency
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