Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

III_BLOOD_IMMUN

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 D50-D89
Hospital discharge: ICD-9 28
Hospital discharge: ICD-8 28
Cause of death: ICD-10 D50-D89
Cause of death: ICD-9 28
Cause of death: ICD-8 28

31277

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

31277

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Check minimum number of events None

31277

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Include endpoints None

31277

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III_BLOOD_IMMUN

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

Summary Statistics

Key figures

All Female Male
Number of individuals 30182 16921 13261
Unadjusted prevalence (%) 9.78 9.75 9.82
Mean age at first event (years) 54.91 50.94 59.98

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 4.02 [3.52, 4.60] 5.9e-91 5232
15 years 0.01 1.65 [1.45, 1.87] 1.8e-14 1541
5 years 0.00 4.57 [4.15, 5.04] <1e-100 1825
1 year 0.00 16.36 [14.57, 18.37] <1e-100 1558

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: III_BLOOD_IMMUN – Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
GWS hits:

Survival analyses between endpoints

Plot

before Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
after Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

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Drugs most likely to be purchased after Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism