Type 1 diabetes, wide definition, subgroup 2

T1D_WIDE2

type I diabetes mellitus: A chronic condition characterized by minimal or absent production of insulin by the pancreas.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions

not PANCREATITIS
and not INSULIN_INTER_AND_LONG
and KELA_DIAB_INSUL
and INSULIN_SHORTFAST

491

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

262

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T1D_WIDE2

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 250 121 129
Unadjusted prevalence (%) 0.08 0.07 0.10
Mean age at first event (years) 38.57 37.61 39.47

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 4.14 [2.91, 5.90] 3.5e-15 80
15 years 0.02 3.24 [2.25, 4.66] 2.7e-10 53
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: T1D_WIDE2 – Type 1 diabetes, wide definition, subgroup 2
GWS hits: 0

Survival analyses between endpoints

Plot

before Type 1 diabetes, wide definition, subgroup 2
after Type 1 diabetes, wide definition, subgroup 2

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Drugs most likely to be purchased after Type 1 diabetes, wide definition, subgroup 2