Gestational [pregnancy-induced] hypertension

O15_GESTAT_HYPERT

preeclampsia: Preeclampsia is a hypertensive disorder of pregnancy that is characterized by new-onset hypertension with proteinuria presenting after 20 weeks of gestation, and depending on mild or severe forms may initially present with severe headache, visual disturbances, and hyperreflexia.

Endpoint definition

FinnGen phenotype data

321302 individuals

diagram downward connector
diagram bullet

Apply sex-specific rule

Sex only females

180574

diagram downward connector

Check conditions None

180574

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 O13
Hospital discharge: ICD-9 6423
Hospital discharge: ICD-8 63701
Cause of death: ICD-10 O13
Cause of death: ICD-9 6423
Cause of death: ICD-8 63701

-

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

-

diagram downward connector

Check minimum number of events None

-

diagram downward connector

Include endpoints None

6731

diagram downward connector
O15_GESTAT_HYPERT

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF5
Parent code in ICD-10 O10-O16
Name in latin Hypertensio gestationalis sine proteinuria significanti

Summary Statistics

Key figures

All Female Male
Number of individuals 6562 6562 -
Unadjusted prevalence (%) 2.13 3.78 -
Mean age at first event (years) 30.05 30.05 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 1.08 [0.77, 1.53] 6.6e-1 117
15 years 0.01 0.90 [0.61, 1.34] 6.2e-1 50
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: O15_GESTAT_HYPERT – Gestational [pregnancy-induced] hypertension
GWS hits: 3

Survival analyses between endpoints

Plot

before Gestational [pregnancy-induced] hypertension
after Gestational [pregnancy-induced] hypertension

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Gestational [pregnancy-induced] hypertension