Diseases of appendix

K11_APPENDIX

appendicitis: Acute inflammation of the vermiform appendix.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 K35-K38
Cause of death: ICD-10 K35-K38

12004

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

12004

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Check minimum number of events None

12004

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Include endpoints

25265

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K11_APPENDIX

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 24557 13409 11148
Unadjusted prevalence (%) 7.96 7.73 8.26
Mean age at first event (years) 33.96 32.26 36.00

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 1.02 [0.84, 1.24] 8.2e-1 1321
15 years 0.00 0.77 [0.65, 0.92] 3.9e-3 596
5 years 0.00 1.09 [0.90, 1.31] 3.8e-1 196
1 year 0.00 1.92 [1.44, 2.55] 6.6e-6 63

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: K11_APPENDIX – Diseases of appendix
GWS hits: 7

Survival analyses between endpoints

Plot

before Diseases of appendix
after Diseases of appendix

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Diseases of appendix