Acute appendicitis

K11_APPENDACUT

appendicitis: Acute inflammation of the vermiform appendix.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 K35
Hospital discharge: ICD-9 540
Hospital discharge: ICD-8 540
Cause of death: ICD-10 K35
Cause of death: ICD-9 540
Cause of death: ICD-8 540

23403

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

23403

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Check minimum number of events None

23403

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Include endpoints None

23403

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K11_APPENDACUT

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 K35-K38
Name in latin Appendicitis acuta

Summary Statistics

Key figures

All Female Male
Number of individuals 22753 12314 10439
Unadjusted prevalence (%) 7.37 7.10 7.73
Mean age at first event (years) 34.37 32.65 36.40

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 1.08 [0.90, 1.29] 4.1e-1 1208
15 years 0.00 0.80 [0.68, 0.95] 8.6e-3 546
5 years 0.00 1.13 [0.94, 1.36] 2.1e-1 184
1 year 0.00 2.03 [1.52, 2.70] 1.3e-6 60

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: K11_APPENDACUT – Acute appendicitis
GWS hits: 6

Survival analyses between endpoints

Plot

before Acute appendicitis
after Acute appendicitis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Acute appendicitis