Vitamin A deficiency

E4_VIT_A_DEF

ascorbic acid deficiency: A condition due to a dietary deficiency of ascorbic acid (vitamin C), characterized by malaise, lethargy, and weakness. As the disease progresses, joints, muscles, and subcutaneous tissues may become the sites of hemorrhage. Ascorbic acid deficiency frequently develops into scurvy in young children fed unsupplemented cow's milk exclusively during their first year. It develops also commonly in chronic alcoholism. (Cecil Textbook of Medicine, 19th ed, p1177)

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E50

Hospital discharge: ICD-9 264

Hospital discharge: ICD-8 260

Cause of death: ICD-10 E50

Cause of death: ICD-9 264

Cause of death: ICD-8 260

100

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

E4_VIT_A_DEF

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 E50-E64

Name in latin Deficientia vitamini A

Similar endpoints

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List of similar endpoints to Vitamin A deficiency based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	89	61	28
Unadjusted prevalence (%)	0.03	0.04	0.02
Mean age at first event (years)	50.11	45.23	60.73

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_VIT_A_DEF – Vitamin A deficiency
GWS hits:

Survival analyses between endpoints

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Plot

before Vitamin A deficiency
after Vitamin A deficiency

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Table

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Drugs most likely to be purchased after Vitamin A deficiency

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