Vitamin deficiency


ascorbic acid deficiency: A condition due to a dietary deficiency of ascorbic acid (vitamin C), characterized by malaise, lethargy, and weakness. As the disease progresses, joints, muscles, and subcutaneous tissues may become the sites of hemorrhage. Ascorbic acid deficiency frequently develops into scurvy in young children fed unsupplemented cow's milk exclusively during their first year. It develops also commonly in chronic alcoholism. (Cecil Textbook of Medicine, 19th ed, p1177)

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 E50, E51, E52, E52+F02.89, E53, E54, E55, E56
Cause of death: ICD-10 E50, E51, E52, E52+F02.89, E53, E54, E55, E56


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10


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Check minimum number of events None


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Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 1003 590 413
Unadjusted prevalence (%) 0.33 0.34 0.31
Mean age at first event (years) 52.85 50.23 56.60


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.35 [1.26, 4.38] 7.2e-3 160
15 years 0.01 1.22 [0.63, 2.37] 5.5e-1 74
5 years 0.00 2.71 [1.65, 4.45] 8.3e-5 50
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: E4_VIT_DEF – Vitamin deficiency
GWS hits: 0

Survival analyses between endpoints


before Vitamin deficiency
after Vitamin deficiency

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Drugs most likely to be purchased after Vitamin deficiency