Crohn's disease of small interstine

CHRONSMALL

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 K50.0
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 K50.0
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

1542

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1542

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Check minimum number of events None

1542

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Include endpoints None

1542

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CHRONSMALL

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K50
Name in latin Morbus Crohn intestini tenuis

Summary Statistics

Key figures

All Female Male
Number of individuals 1501 847 654
Unadjusted prevalence (%) 0.49 0.49 0.48
Mean age at first event (years) 44.50 42.50 47.08

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 5.26 [3.16, 8.74] 1.5e-10 57
15 years 0.01 2.36 [1.31, 4.26] 4.3e-3 21
5 years 0.01 6.17 [3.54, 10.73] 1.2e-10 19
1 year 0.00 14.76 [7.08, 30.81] 7.3e-13 10

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: CHRONSMALL – Crohn's disease of small interstine
GWS hits: 4

Survival analyses between endpoints

Plot

before Crohn's disease of small interstine
after Crohn's disease of small interstine

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Drugs most likely to be purchased after Crohn's disease of small interstine