Non-small cell lung cancer

C3_NSCLC

non-small cell lung carcinoma: A group of at least three distinct histological types of lung cancer, including non-small cell squamous cell carcinoma, adenocarcinoma, and large cell carcinoma. Non-small cell lung carcinomas have a poor response to conventional chemotherapy.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions

HLP_C3_NSCLC

27

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Filter registries

Cause of death: ICD-10 C34
Cause of death: ICD-9 162
Cause of death: ICD-8 162
Cancer registry: Topography ICD-O-3 C34
Cancer registry: Morphology ICD-O-3 8046
Cancer registry: Behaviour codes 3

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints None

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C3_NSCLC

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF4

Summary Statistics

Key figures

All Female Male
Number of individuals 26 6 20
Unadjusted prevalence (%) 0.01 0.00 0.01
Mean age at first event (years) 73.29 71.22 73.92

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: C3_NSCLC – Non-small cell lung cancer
GWS hits:

Survival analyses between endpoints

Plot

before Non-small cell lung cancer
after Non-small cell lung cancer

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Drugs most likely to be purchased after Non-small cell lung cancer