Type1 diabetes, definitions combined, early onset

PheWeb

T1D_EARLY

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries None

Check pre-conditions, main-only, mode, ICD version

Pre-conditions EVENT_AGE < 20

Check minimum number of events None

Include endpoints

T1D

2593

T1D_EARLY

Extra metadata

First used in FinnGen datafreeze DF7

Similar endpoints

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List of similar endpoints to Type1 diabetes, definitions combined, early onset based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	2535	1308	1227
Unadjusted prevalence (%)	0.82	0.75	0.91
Mean age at first event (years)	9.57	9.56	9.57

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.17	14.57 [6.35, 33.42]	2.5e-10	62
15 years	0.10	17.79 [7.63, 41.50]	2.7e-11	37
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: T1D_EARLY – Type1 diabetes, definitions combined, early onset
GWS hits:

Survival analyses between endpoints

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Plot

before Type1 diabetes, definitions combined, early onset
after Type1 diabetes, definitions combined, early onset

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Table

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Drugs most likely to be purchased after Type1 diabetes, definitions combined, early onset

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