Second line medication for Crohns disease

PheWeb

RX_CROHN_2NDLINE

No definition available.

Endpoint definition

↥

FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Medicine purchases: ATC L04AX|L01BB02

19425

Check pre-conditions, main-only, mode, ICD version None

16283

Check minimum number of events

Min. number of events 3

16283

Include endpoints None

16283

RX_CROHN_2NDLINE

Extra metadata

First used in FinnGen datafreeze DF5

Similar endpoints

↥

List of similar endpoints to Second line medication for Crohns disease based on the number of shared cases.

Broader endpoints:

Any prescribed medicine buy

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

↥

Key figures

	All	Female	Male
Number of individuals	15801	9851	5950
Unadjusted prevalence (%)	5.12	5.68	4.41
Mean age at first event (years)	50.72	49.93	52.04

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.36 [1.88, 2.95]	8.7e-14	772
15 years	0.01	1.55 [1.25, 1.92]	6.4e-5	415
5 years	0.00	3.18 [2.61, 3.88]	3.4e-30	260
1 year	0.00	3.27 [2.38, 4.50]	3.1e-13	51

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: RX_CROHN_2NDLINE – Second line medication for Crohns disease
GWS hits: 13

Survival analyses between endpoints

↥

Plot

before Second line medication for Crohns disease
after Second line medication for Crohns disease

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Second line medication for Crohns disease

↥