Azathioprine

RX_L04AX01

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Medicine purchases: ATC L04AX01

6198

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Check pre-conditions, main-only, mode, ICD version None

4246

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Check minimum number of events

Min. number of events 3

4246

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Include endpoints None

4246

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RX_L04AX01

Extra metadata

First used in FinnGen datafreeze DF4

Summary Statistics

Key figures

All Female Male
Number of individuals 4128 2358 1770
Unadjusted prevalence (%) 1.34 1.36 1.31
Mean age at first event (years) 44.32 43.56 45.33

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 3.48 [2.33, 5.19] 1.1e-9 247
15 years 0.01 2.08 [1.40, 3.10] 3.1e-4 118
5 years 0.00 3.72 [2.42, 5.74] 2.6e-9 72
1 year 0.00 3.84 [2.06, 7.14] 2.2e-5 14

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: RX_L04AX01 – Azathioprine
GWS hits:

Survival analyses between endpoints

Plot

before Azathioprine
after Azathioprine

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