6-mercaptopurine

PheWeb

RX_L01BB02

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Medicine purchases: ATC L01BB02

835

Check pre-conditions, main-only, mode, ICD version None

511

Check minimum number of events

Min. number of events 3

511

Include endpoints None

511

RX_L01BB02

Extra metadata

First used in FinnGen datafreeze DF4

Similar endpoints

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List of similar endpoints to 6-mercaptopurine based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	490	278	212
Unadjusted prevalence (%)	0.16	0.16	0.16
Mean age at first event (years)	42.82	42.20	43.62

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.14	10.97 [3.62, 33.24]	2.3e-5	21
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: RX_L01BB02 – 6-mercaptopurine
GWS hits:

Survival analyses between endpoints

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Plot

before 6-mercaptopurine
after 6-mercaptopurine

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after 6-mercaptopurine

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