Other (seronegative) rheumatoid arthritis, wide


rheumatoid arthritis: A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 M06
Hospital discharge: ICD-9 7140B|7148|7142
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 M06
Cause of death: ICD-9 7140B|7148|7142
Cause of death: ICD-8 $!$


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9


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Check minimum number of events None


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Include endpoints None


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Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 M05-M14
Name in latin Alia arthritis rheumatoides

Summary Statistics

Key figures

All Female Male
Number of individuals 4795 3307 1488
Unadjusted prevalence (%) 1.55 1.91 1.10
Mean age at first event (years) 54.74 53.07 58.45


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.41 [1.50, 3.86] 2.8e-4 531
15 years 0.01 1.35 [0.82, 2.20] 2.4e-1 230
5 years 0.00 2.88 [2.08, 3.98] 1.8e-10 154
1 year 0.00 7.06 [5.00, 9.97] 1.1e-28 76

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: RHEUMA_OTHER_WIDE – Other (seronegative) rheumatoid arthritis, wide
GWS hits: 4

Survival analyses between endpoints


before Other (seronegative) rheumatoid arthritis, wide
after Other (seronegative) rheumatoid arthritis, wide

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Drugs most likely to be purchased after Other (seronegative) rheumatoid arthritis, wide