Rheumatoid lung disease

RHEUMAT_LUNG

adult-onset Still's disease: adult-onset Still disease (AOSD) is a rare inflammatory multisystem disorder characterized clinically by fever of unknown origin, arthralgia or arthritis, hyperleucocytosis, and typical skin rash.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 J99.0*, J99.0*M05.1, M05.1+J99.0

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 J99.0*, J99.0*M05.1, M05.1+J99.0

Cause of death: ICD-9 $!$

Cause of death: ICD-8 $!$

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

RHEUMAT_LUNG

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Rheumatoid lung disease based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	74	31	43
Unadjusted prevalence (%)	0.02	0.02	0.03
Mean age at first event (years)	67.71	65.89	69.01

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: RHEUMAT_LUNG – Rheumatoid lung disease
GWS hits:

Survival analyses between endpoints

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Plot

before Rheumatoid lung disease
after Rheumatoid lung disease

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Rheumatoid lung disease

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