Left ventricular outflow tract obstruction, narrow definition

PheWeb

Q17_LVOTO_NARROW

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 Q23, Q24.4, Q25.1, Q25.20, Q25.3, Q25.40

Hospital discharge: ICD-9 7463A|7464A|7463D|7465A|7466A|7467A|7468X|7463X|7471A|7472B|7471B

Hospital discharge: ICD-8 $!$

Hospital discharge: excluded ICD-10 Q90|Q91|Q92|Q93|Q96|Q8780|Q8781|Q8782|Q8783|Q8784|Q8786|Q8788|Q85|Q796|Q874|Q875

Hospital discharge: excluded ICD-9 758|7595|75683

Cause of death: ICD-10 Q23, Q24.4, Q25.1, Q25.20, Q25.3, Q25.40

Cause of death: ICD-9 7463A|7464A|7463D|7465A|7466A|7467A|7468X|7463X|7471A|7472B|7471B

Cause of death: ICD-8 $!$

Cause of death: excluded ICD-10 Q90|Q91|Q92|Q93|Q96|Q8780|Q8781|Q8782|Q8783|Q8784|Q8786|Q8788|Q85|Q796|Q874|Q875

Cause of death: excluded ICD-9 758|7595|75683

979

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

979

Check minimum number of events None

979

Include endpoints None

979

Q17_LVOTO_NARROW

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF7

Similar endpoints

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List of similar endpoints to Left ventricular outflow tract obstruction, narrow definition based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	939	344	595
Unadjusted prevalence (%)	0.30	0.20	0.44
Mean age at first event (years)	40.49	36.28	42.92

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	4.09 [1.99, 8.41]	1.3e-4	41
15 years	0.01	1.63 [0.72, 3.68]	2.4e-1	12
5 years	0.01	4.89 [2.40, 9.96]	1.2e-5	11
1 year	0.00	24.09 [11.77, 49.34]	3.3e-18	11

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: Q17_LVOTO_NARROW – Left ventricular outflow tract obstruction, narrow definition
GWS hits:

Survival analyses between endpoints

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Plot

before Left ventricular outflow tract obstruction, narrow definition
after Left ventricular outflow tract obstruction, narrow definition

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Table

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Drugs most likely to be purchased after Left ventricular outflow tract obstruction, narrow definition

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