Congenital malformations, deformations and chromosomal abnormalities

PheWeb

Q17_CONGEN_MALFO_DEFORMAT_CHROMOSOMAL_ABNORMALITI

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 Q00-Q99

Hospital discharge: ICD-9 7[4-5]

Hospital discharge: ICD-8 7[4-5]

Cause of death: ICD-10 Q00-Q99

Cause of death: ICD-9 7[4-5]

Cause of death: ICD-8 7[4-5]

19378

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

19378

Check minimum number of events None

19378

Include endpoints None

19378

Q17_CONGEN_MALFO_DEFORMAT_CHROMOSOMAL_ABNORMALITI

Extra metadata

Level in the ICD hierarchy 1

Special XVII_MALFORMAT_ABNORMAL

First used in FinnGen datafreeze DF4

Similar endpoints

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List of similar endpoints to Congenital malformations, deformations and chromosomal abnormalities based on the number of shared cases.

Broader endpoints:

Any ICDMAIN event in hilmo or causes of death

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	18670	11344	7326
Unadjusted prevalence (%)	6.05	6.54	5.43
Mean age at first event (years)	29.80	30.26	29.07

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.73 [1.40, 2.14]	5.0e-7	864
15 years	0.01	1.27 [1.05, 1.55]	1.4e-2	406
5 years	0.00	2.04 [1.66, 2.49]	5.2e-12	162
1 year	0.00	4.01 [3.00, 5.37]	1.0e-20	60

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: Q17_CONGEN_MALFO_DEFORMAT_CHROMOSOMAL_ABNORMALITI – Congenital malformations, deformations and chromosomal abnormalities
GWS hits:

Survival analyses between endpoints

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Plot

before Congenital malformations, deformations and chromosomal abnormalities
after Congenital malformations, deformations and chromosomal abnormalities

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Table

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Drugs most likely to be purchased after Congenital malformations, deformations and chromosomal abnormalities

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