Pneumonias (Asthma/COPD co-morbidities)

PNEUMONIA

pneumonia: An acute, acute and chronic, or chronic inflammation focally or diffusely affecting the lung parenchyma, caused by an infection in one or both of the lungs (by bacteria, viruses, fungi, or mycoplasma.). Symptoms include cough, shortness of breath, fevers, chills, chest pain, headache, sweating, and weakness.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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PNEUMONIA

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Pneumonias (Asthma/COPD co-morbidities) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 43583 18652 24931
Unadjusted prevalence (%) 14.13 10.75 18.46
Mean age at first event (years) 55.84 52.05 58.68

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.09 7.70 [7.02, 8.44] <1e-100 11590
15 years 0.01 2.70 [2.44, 2.98] 4.1e-85 2434
5 years 0.01 7.17 [6.60, 7.79] <1e-100 3258
1 year 0.01 40.98 [36.83, 45.60] <1e-100 5451

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: PNEUMONIA – Pneumonias (Asthma/COPD co-morbidities)
GWS hits:

Survival analyses between endpoints

Plot

before Pneumonias (Asthma/COPD co-morbidities)
after Pneumonias (Asthma/COPD co-morbidities)

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Drugs most likely to be purchased after Pneumonias (Asthma/COPD co-morbidities)