COPD/asthma/ILD related infections

PULM_INFECTIONS

pasteurellosis: Infections with bacteria of the genus pasteurella.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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PULM_INFECTIONS

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to COPD/asthma/ILD related infections based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 90105 41741 48364
Unadjusted prevalence (%) 29.20 24.05 35.82
Mean age at first event (years) 43.31 43.26 43.36

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 5.39 [4.95, 5.86] <1e-100 13504
15 years 0.01 2.37 [2.16, 2.60] 1.3e-72 3525
5 years 0.01 5.83 [5.39, 6.31] <1e-100 3828
1 year 0.01 29.96 [26.88, 33.39] <1e-100 5196

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: PULM_INFECTIONS – COPD/asthma/ILD related infections
GWS hits: 2

Survival analyses between endpoints

Plot

before COPD/asthma/ILD related infections
after COPD/asthma/ILD related infections

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Drugs most likely to be purchased after COPD/asthma/ILD related infections