Dementia due to Parkinsons disease

PD_DEMENTIA

obsolete_dementia: ['An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.']

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 F02.3*, F02.39*

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 F02.3*, F02.39*

Cause of death: ICD-9 $!$

Cause of death: ICD-8 $!$

401

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

401

Check minimum number of events None

401

Include endpoints None

401

PD_DEMENTIA

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Dementia due to Parkinsons disease based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	390	128	262
Unadjusted prevalence (%)	0.13	0.07	0.19
Mean age at first event (years)	75.53	76.59	75.02

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: PD_DEMENTIA – Dementia due to Parkinsons disease
GWS hits: 1

Survival analyses between endpoints

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Plot

before Dementia due to Parkinsons disease
after Dementia due to Parkinsons disease

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Dementia due to Parkinsons disease

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