Nonalcoholic steatohepatitis


Hepatitis, Alcoholic: INFLAMMATION of the LIVER due to ALCOHOL ABUSE. It is characterized by NECROSIS of HEPATOCYTES, infiltration by NEUTROPHILS, and deposit of MALLORY BODIES. Depending on its severity, the inflammatory lesion may be reversible or progress to LIVER CIRRHOSIS.

Endpoint definition

FinnGen phenotype data

321302 individuals

diagram downward connector

Apply sex-specific rule None


diagram downward connector

Check conditions None


diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 K73.80
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 K73.80
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$


diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9


diagram downward connector

Check minimum number of events None


diagram downward connector

Include endpoints None


diagram downward connector

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K73

Summary Statistics

Key figures

All Female Male
Number of individuals 99 62 37
Unadjusted prevalence (%) 0.03 0.04 0.03
Mean age at first event (years) 56.95 57.79 55.55


Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: NASH – Nonalcoholic steatohepatitis
GWS hits:

Survival analyses between endpoints


before Nonalcoholic steatohepatitis
after Nonalcoholic steatohepatitis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Nonalcoholic steatohepatitis