Wegener granulomatosis

M13_WEGENER

Granulomatosis with Polyangiitis: A small-vessel necrotizing vasculitis characterised by the association of inflammation of the vessel wall and peri- and extravascular granulomatosis.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 M31.3
Hospital discharge: ICD-9 4464
Hospital discharge: ICD-8 4462
Cause of death: ICD-10 M31.3
Cause of death: ICD-9 4464
Cause of death: ICD-8 4462

380

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

362

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Check minimum number of events None

362

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Include endpoints None

362

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M13_WEGENER

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M31
Name in latin Granulomatosis Wegener

Summary Statistics

Key figures

All Female Male
Number of individuals 350 182 168
Unadjusted prevalence (%) 0.11 0.10 0.12
Mean age at first event (years) 52.98 51.65 54.43

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: M13_WEGENER – Wegener granulomatosis
GWS hits: 0

Survival analyses between endpoints

Plot

before Wegener granulomatosis
after Wegener granulomatosis

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Drugs most likely to be purchased after Wegener granulomatosis