Aortic arch syndrome [Takayasu]


Takayasu arteritis: Takayasu arteritis (TAK) is a rare inflammatory large-vessel vasculitis primarily affecting the aorta and its major branches, but also other large vessels, causing stenosis, occlusion, or aneurysm.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 M31.4
Hospital discharge: ICD-9 4467
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 M31.4
Cause of death: ICD-9 4467
Cause of death: ICD-8 $!$


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9


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Check minimum number of events None


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Include endpoints None


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Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M31
Name in latin Syndroma arcus aortae

Summary Statistics

Key figures

All Female Male
Number of individuals 35 27 8
Unadjusted prevalence (%) 0.01 0.02 0.01
Mean age at first event (years) 47.31 46.02 51.66


Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: M13_TAKAYASU – Aortic arch syndrome [Takayasu]
GWS hits:

Survival analyses between endpoints


before Aortic arch syndrome [Takayasu]
after Aortic arch syndrome [Takayasu]

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Drugs most likely to be purchased after Aortic arch syndrome [Takayasu]