Spinal stenosis

DOID EFO MESH SNOMED PheWeb

M13_SPINSTENOSIS

spinal stenosis: Narrowing of the spinal canal.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 M48.0

Hospital discharge: ICD-9 7230A|7240

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 M48.0

Cause of death: ICD-9 7230A|7240

Cause of death: ICD-8 $!$

14785

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

14722

Check minimum number of events None

14722

Include endpoints None

14722

M13_SPINSTENOSIS

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 M48

Name in latin Stenosis spinalis

Similar endpoints

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List of similar endpoints to Spinal stenosis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	14389	7654	6735
Unadjusted prevalence (%)	4.66	4.41	4.99
Mean age at first event (years)	63.68	63.44	63.95

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.03 [1.73, 2.39]	6.2e-18	1473
15 years	0.01	1.24 [1.05, 1.48]	1.3e-2	780
5 years	0.00	1.89 [1.61, 2.21]	1.6e-15	403
1 year	0.00	2.91 [2.32, 3.65]	1.6e-20	119

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_SPINSTENOSIS – Spinal stenosis
GWS hits: 6

Survival analyses between endpoints

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Plot

before Spinal stenosis
after Spinal stenosis

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Table

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Drugs most likely to be purchased after Spinal stenosis

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