Other specified disorders of muscle

M13_MUSCLEDISNAS

myopathy: a disease of the muscle in which the muscle fibers do not function properly. This results in muscular weakness.

Endpoint definition

↥

FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 M62.8, M62.9

Hospital discharge: ICD-9 728[8-9]

Hospital discharge: ICD-8 733

Hospital discharge: excluded ICD-8 733|777[0-1]|73390

Cause of death: ICD-10 M62.8, M62.9

Cause of death: ICD-9 728[8-9]

Cause of death: ICD-8 733

Cause of death: excluded ICD-8 733|777[0-1]|73390

2733

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

664

Check minimum number of events None

664

Include endpoints None

664

M13_MUSCLEDISNAS

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Similar endpoints

↥

List of similar endpoints to Other specified disorders of muscle based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

↥

Key figures

	All	Female	Male
Number of individuals	644	326	318
Unadjusted prevalence (%)	0.21	0.19	0.24
Mean age at first event (years)	43.48	44.45	42.49

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	3.22 [1.74, 5.97]	2.0e-4	70
15 years	0.01	1.79 [1.00, 3.20]	5.0e-2	24
5 years	0.00	2.48 [1.24, 4.96]	1.0e-2	10
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: M13_MUSCLEDISNAS – Other specified disorders of muscle
GWS hits: 0

Survival analyses between endpoints

↥

Plot

before Other specified disorders of muscle
after Other specified disorders of muscle

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Other specified disorders of muscle

↥