Disorders of muscles

M13_MUSCLE

myositis: An inflammatory disease involving a pathogenic inflammatory response in the muscle tissue.

Endpoint definition

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FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Hospital Discharge: ICD-10 M60-M63
Cause of death: ICD-10 M60-M63

1863

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

1863

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Check minimum number of events None

1863

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M13_MUSCLE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Disorders of muscles based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

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Summary Statistics

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Key figures

All Female Male
Number of individuals 2252 1186 1066
Unadjusted prevalence (%) 0.73 0.68 0.79
Mean age at first event (years) 48.93 47.88 50.09

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.21 [0.44, 3.31] 7.2e-1 193
15 years 0.01 0.82 [0.34, 1.96] 6.5e-1 78
5 years 0.00 1.93 [1.01, 3.69] 4.6e-2 49
1 year 0.00 8.36 [4.51, 15.50] 1.6e-11 40

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_MUSCLE – Disorders of muscles
GWS hits: 0

Survival analyses between endpoints

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Plot

before Disorders of muscles
after Disorders of muscles

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Drugs most likely to be purchased after Disorders of muscles

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