Soft tissue disorders


musculoskeletal system disease: A disease involving the musculoskeletal system. [database_cross_reference: MONDO:DesignPattern]

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 M60-M79
Cause of death: ICD-10 M60-M79


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10


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Check minimum number of events None


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Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Soft tissue disorders based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 77694 45830 31864
Unadjusted prevalence (%) 25.18 26.41 23.60
Mean age at first event (years) 50.85 49.35 53.00


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.27 [1.14, 1.42] 1.2e-5 5049
15 years 0.01 0.92 [0.83, 1.01] 8.4e-2 2477
5 years 0.00 1.57 [1.42, 1.73] 1.3e-19 1131
1 year 0.00 3.10 [2.69, 3.57] 6.1e-56 419

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: M13_SOFTTISSUE – Soft tissue disorders
GWS hits: 6

Survival analyses between endpoints


before Soft tissue disorders
after Soft tissue disorders

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Drugs most likely to be purchased after Soft tissue disorders