Soft tissue disorders

M13_SOFTTISSUE

musculoskeletal system disease: A disease involving the musculoskeletal system. [database_cross_reference: MONDO:DesignPattern]

Endpoint definition

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FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 M60-M79
Cause of death: ICD-10 M60-M79

75283

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

75283

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Check minimum number of events None

75283

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M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Soft tissue disorders based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 77694 45830 31864
Unadjusted prevalence (%) 25.18 26.41 23.60
Mean age at first event (years) 50.85 49.35 53.00

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.27 [1.14, 1.42] 1.2e-5 5049
15 years 0.01 0.92 [0.83, 1.01] 8.4e-2 2477
5 years 0.00 1.57 [1.42, 1.73] 1.3e-19 1131
1 year 0.00 3.10 [2.69, 3.57] 6.1e-56 419

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_SOFTTISSUE – Soft tissue disorders
GWS hits: 6

Survival analyses between endpoints

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Plot

before Soft tissue disorders
after Soft tissue disorders

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Drugs most likely to be purchased after Soft tissue disorders

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