Ankylosing hyperostosis [Forestier]


diffuse idiopathic skeletal hyperostosis: This syndrome is characterized by the association of ankylosing vertebral hyperostosis with hyperkeratosis of the soles and palms.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 M48.1
Hospital discharge: ICD-9 7216
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 M48.1
Cause of death: ICD-9 7216
Cause of death: ICD-8 $!$


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9


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Check minimum number of events None


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Include endpoints None


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Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M48
Name in latin Hyperostosis ancylopoetica

Summary Statistics

Key figures

All Female Male
Number of individuals 283 123 160
Unadjusted prevalence (%) 0.09 0.07 0.12
Mean age at first event (years) 58.29 57.25 59.09


Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: M13_FORESTIER – Ankylosing hyperostosis [Forestier]
GWS hits: 0

Survival analyses between endpoints


before Ankylosing hyperostosis [Forestier]
after Ankylosing hyperostosis [Forestier]

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Drugs most likely to be purchased after Ankylosing hyperostosis [Forestier]