Other and unspecified acute skin changes due to ultraviolet radiation

L12_OTHACUSKINSUNNAS

phototoxic dermatitis: a form of allergic contact dermatitis in which the allergen must be activated by light to sensitize the allergic response, and to cause a rash or other systemic effects on subsequent exposure. The second and subsequent exposures produce photoallergic skin conditions which are often eczematous. In rare cases the victims die.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 L56.8, L56.9

Hospital discharge: ICD-9 6927

Hospital discharge: ICD-8 6928

Hospital discharge: excluded ICD-9 6927F

Cause of death: ICD-10 L56.8, L56.9

Cause of death: ICD-9 6927

Cause of death: ICD-8 6928

Cause of death: excluded ICD-9 6927F

646

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

595

Check minimum number of events None

595

Include endpoints None

595

L12_OTHACUSKINSUNNAS

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other and unspecified acute skin changes due to ultraviolet radiation based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

All

Female

Male

Number of individuals

580

258

322

Unadjusted prevalence (%)

0.19

0.15

0.24

Mean age at first event (years)

39.82

39.81

39.82

?

Follow-up

Amount of time to look for the endpoint since entering the study. This is either either 1, 5, 15 years or the full study time from 1998 to 2019.

Absolute risk

Estimates the probability of dying from the current endpoint. Check the Documentation page for Mortality: absolute risk to get more details.

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Measures how much the risk of dying increases (HR > 1) or decreases (HR < 1).

Number of individuals (N)

Number of individuals having the current endpoint and died during the follow-up time.
Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.01	0.99 [0.55, 1.81]	9.8e-1	87
15 years	0.00	0.75 [0.44, 1.29]	3.0e-1	40
5 years	0.00	1.31 [0.72, 2.38]	3.7e-1	18
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_OTHACUSKINSUNNAS – Other and unspecified acute skin changes due to ultraviolet radiation
GWS hits: 0

Survival analyses between endpoints

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Plot

before Other and unspecified acute skin changes due to ultraviolet radiation
after Other and unspecified acute skin changes due to ultraviolet radiation

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Table

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Drugs most likely to be purchased after Other and unspecified acute skin changes due to ultraviolet radiation

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