Other and unspecified acute skin changes due to ultraviolet radiation

L12_OTHACUSKINSUNNAS

phototoxic dermatitis: a form of allergic contact dermatitis in which the allergen must be activated by light to sensitize the allergic response, and to cause a rash or other systemic effects on subsequent exposure. The second and subsequent exposures produce photoallergic skin conditions which are often eczematous. In rare cases the victims die.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 L56.8, L56.9

Hospital discharge: ICD-9 6927

Hospital discharge: ICD-8 6928

Hospital discharge: excluded ICD-9 6927F

Cause of death: ICD-10 L56.8, L56.9

Cause of death: ICD-9 6927

Cause of death: ICD-8 6928

Cause of death: excluded ICD-9 6927F

646

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

595

Check minimum number of events None

595

Include endpoints None

595

L12_OTHACUSKINSUNNAS

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other and unspecified acute skin changes due to ultraviolet radiation based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	580	258	322
Unadjusted prevalence (%)	0.19	0.15	0.24
Mean age at first event (years)	39.82	39.81	39.82

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.01	0.99 [0.55, 1.81]	9.8e-1	87
15 years	0.00	0.75 [0.44, 1.29]	3.0e-1	40
5 years	0.00	1.31 [0.72, 2.38]	3.7e-1	18
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_OTHACUSKINSUNNAS – Other and unspecified acute skin changes due to ultraviolet radiation
GWS hits: 0

Survival analyses between endpoints

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Plot

before Other and unspecified acute skin changes due to ultraviolet radiation
after Other and unspecified acute skin changes due to ultraviolet radiation

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Table

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Drugs most likely to be purchased after Other and unspecified acute skin changes due to ultraviolet radiation

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