Other acute skin changes due to ultraviolet radiation

DOID EFO MESH SNOMED PheWeb

L12_OTHACUSKINSUN

phototoxic dermatitis: a form of allergic contact dermatitis in which the allergen must be activated by light to sensitize the allergic response, and to cause a rash or other systemic effects on subsequent exposure. The second and subsequent exposures produce photoallergic skin conditions which are often eczematous. In rare cases the victims die.

Endpoint definition

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FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 L56

Cause of death: ICD-10 L56

353

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

353

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Check minimum number of events None

353

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Include endpoints

L12_DRUGPHOTOALL

L12_PHOTOCONTDERMAT

L12_SOLURTICARIA

L12_POLYMORPHLIGHTERUPT

L12_OTHACUSKINSUNNAS

796

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L12_OTHACUSKINSUN

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 L55-L59

Name in latin Aliae commutationes acutae cutis e radiatione ultraviolacea

Similar endpoints

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List of similar endpoints to Other acute skin changes due to ultraviolet radiation based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	774	401	373
Unadjusted prevalence (%)	0.25	0.23	0.28
Mean age at first event (years)	41.27	41.39	41.14

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.61 [0.79, 3.29]	1.9e-1	97
15 years	0.01	1.13 [0.62, 2.05]	6.9e-1	45
5 years	0.00	2.08 [1.16, 3.70]	1.3e-2	22
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_OTHACUSKINSUN – Other acute skin changes due to ultraviolet radiation
GWS hits: 0

Survival analyses between endpoints

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Plot

before Other acute skin changes due to ultraviolet radiation
after Other acute skin changes due to ultraviolet radiation

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Table

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Drugs most likely to be purchased after Other acute skin changes due to ultraviolet radiation

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