Skin changes due to chronic exposure to nonionizing radiation

L12_NONIONRADISKIN

photosensitivity disease: Photosensitivity refers to various symptoms, diseases and conditions caused or aggravated by exposure to sunlight.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 L57

Cause of death: ICD-10 L57

8191

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

8191

Check minimum number of events None

8191

Include endpoints

L12_ACTINKERA

L12_ACTINRETICU

L12_CUTRHOMBNUCHA

L12_POIKOLOCIVAT

L12_CUTLAXSEN

L12_ACTINICGRAN

L12_NONIONRADISKINNAS

8216

L12_NONIONRADISKIN

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 L55-L59

Name in latin Commutationes cutis ex expositione chronica radiationi non ionisanti

Similar endpoints

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List of similar endpoints to Skin changes due to chronic exposure to nonionizing radiation based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	7978	4173	3805
Unadjusted prevalence (%)	2.59	2.40	2.82
Mean age at first event (years)	70.87	69.60	72.27

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.68 [1.31, 2.15]	4.9e-5	796
15 years	0.00	0.83 [0.66, 1.04]	1.0e-1	345
5 years	0.00	2.09 [1.74, 2.52]	1.2e-14	344
1 year	0.00	2.02 [1.52, 2.68]	1.4e-6	67

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_NONIONRADISKIN – Skin changes due to chronic exposure to nonionizing radiation
GWS hits: 15

Survival analyses between endpoints

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Plot

before Skin changes due to chronic exposure to nonionizing radiation
after Skin changes due to chronic exposure to nonionizing radiation

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Table

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Drugs most likely to be purchased after Skin changes due to chronic exposure to nonionizing radiation

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