Autism spe

KRA_PSY_AUTISM

autism: A disorder characterized by marked impairments in social interaction and communication accompanied by a pattern of repetitive, stereotyped behaviors and activities. Developmental delays in social interaction and language surface prior to age 3 years.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 F84.0, F84.5
Hospital discharge: ICD-9 2990
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 F84.0, F84.5
Cause of death: ICD-9 2990
Cause of death: ICD-8 $!$

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints None

432

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KRA_PSY_AUTISM

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 407 159 248
Unadjusted prevalence (%) 0.13 0.09 0.18
Mean age at first event (years) 23.78 24.92 23.05

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: KRA_PSY_AUTISM – Autism spe
GWS hits: 1

Survival analyses between endpoints

Plot

before Autism spe
after Autism spe

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