Autism

F5_AUTISM

autism: A disorder characterized by marked impairments in social interaction and communication accompanied by a pattern of repetitive, stereotyped behaviors and activities. Developmental delays in social interaction and language surface prior to age 3 years.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 F84.0, F84.1, F84.5

Hospital discharge: ICD-9 2990

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 F84.0, F84.1, F84.5

Cause of death: ICD-9 2990

Cause of death: ICD-8 $!$

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

446

F5_AUTISM

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Autism based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Autism spe

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	418	164	254
Unadjusted prevalence (%)	0.14	0.09	0.19
Mean age at first event (years)	23.68	24.67	23.04

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_AUTISM – Autism
GWS hits: 1

Survival analyses between endpoints

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Plot

before Autism
after Autism

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Table

Loading survival analyses table

Drugs most likely to be purchased after Autism

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