Pulmonary eosinophilia, not elsewhere classified

J10_PULMEOS

eosinophilic pneumonia: An inflammatory lung disorder characterized by an increased number of eosinophils in the lungs. The majority of cases are idiopathic, without identifiable cause. In a minority of cases, medications, fungal infections, and environmental triggers have been implicated. It manifests as acute or chronic. Acute eosinophilic pneumonia is a severe and rapidly progressing pneumonia that may lead to respiratory failure requiring mechanical ventilation. Chronic eosinophilic pneumonia follows a slower course and manifests as fever, dyspnea, cough, and weight loss.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 J82

Hospital discharge: ICD-9 5183

Hospital discharge: ICD-8 51920

Cause of death: ICD-10 J82

Cause of death: ICD-9 5183

Cause of death: ICD-8 51920

261

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

261

Check minimum number of events None

261

Include endpoints None

261

J10_PULMEOS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 J80-J84

Name in latin Eosinophilia pulmonum non alibi classificata

Similar endpoints

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List of similar endpoints to Pulmonary eosinophilia, not elsewhere classified based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

All

Female

Male

Number of individuals

252

140

112

Unadjusted prevalence (%)

0.08

Mean age at first event (years)

55.52

53.18

58.44

?

Follow-up

Amount of time to look for the endpoint since entering the study. This is either either 1, 5, 15 years or the full study time from 1998 to 2019.

Absolute risk

Estimates the probability of dying from the current endpoint. Check the Documentation page for Mortality: absolute risk to get more details.

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Measures how much the risk of dying increases (HR > 1) or decreases (HR < 1).

Number of individuals (N)

Number of individuals having the current endpoint and died during the follow-up time.
Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.25 [1.01, 5.02]	4.8e-2	42
15 years	0.01	1.42 [0.71, 2.84]	3.2e-1	19
5 years	0.00	3.10 [1.54, 6.27]	1.6e-3	11
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: J10_PULMEOS – Pulmonary eosinophilia, not elsewhere classified
GWS hits: 1

Survival analyses between endpoints

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Plot

before Pulmonary eosinophilia, not elsewhere classified
after Pulmonary eosinophilia, not elsewhere classified

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Table

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Drugs most likely to be purchased after Pulmonary eosinophilia, not elsewhere classified

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