Pulmonary eosinophilia, not elsewhere classified

J10_PULMEOS

eosinophilic pneumonia: An inflammatory lung disorder characterized by an increased number of eosinophils in the lungs. The majority of cases are idiopathic, without identifiable cause. In a minority of cases, medications, fungal infections, and environmental triggers have been implicated. It manifests as acute or chronic. Acute eosinophilic pneumonia is a severe and rapidly progressing pneumonia that may lead to respiratory failure requiring mechanical ventilation. Chronic eosinophilic pneumonia follows a slower course and manifests as fever, dyspnea, cough, and weight loss.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 J82

Hospital discharge: ICD-9 5183

Hospital discharge: ICD-8 51920

Cause of death: ICD-10 J82

Cause of death: ICD-9 5183

Cause of death: ICD-8 51920

261

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

261

Check minimum number of events None

261

Include endpoints None

261

J10_PULMEOS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 J80-J84

Name in latin Eosinophilia pulmonum non alibi classificata

Similar endpoints

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List of similar endpoints to Pulmonary eosinophilia, not elsewhere classified based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	252	140	112
Unadjusted prevalence (%)	0.08	0.08	0.08
Mean age at first event (years)	55.52	53.18	58.44

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.25 [1.01, 5.02]	4.8e-2	42
15 years	0.01	1.42 [0.71, 2.84]	3.2e-1	19
5 years	0.00	3.10 [1.54, 6.27]	1.6e-3	11
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: J10_PULMEOS – Pulmonary eosinophilia, not elsewhere classified
GWS hits: 1

Survival analyses between endpoints

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Plot

before Pulmonary eosinophilia, not elsewhere classified
after Pulmonary eosinophilia, not elsewhere classified

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Table

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Drugs most likely to be purchased after Pulmonary eosinophilia, not elsewhere classified

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