All influenza

J10_INFLUENZA

influenza: An acute viral infection of the respiratory tract, occurring in isolated cases, in epidemics, or in pandemics; it is caused by serologically different strains of viruses (influenzaviruses) designated A, B, and C, has a 3-day incubation period, and usually lasts for 3 to 10 days. It is marked by inflammation of the nasal mucosa, pharynx, and conjunctiva; headache; myalgia; often fever, chills, and prostration; and occasionally involvement of the myocardium or central nervous system.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 J09, J10, J11
Hospital discharge: ICD-9 487
Hospital discharge: ICD-8 47[0-4]
Cause of death: ICD-10 J09, J10, J11
Cause of death: ICD-9 487
Cause of death: ICD-8 47[0-4]

18163

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

6960

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Check minimum number of events None

6960

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Include endpoints None

6960

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J10_INFLUENZA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 6692 2997 3695
Unadjusted prevalence (%) 2.17 1.73 2.74
Mean age at first event (years) 51.70 54.56 49.39

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 3.70 [2.25, 6.08] 2.5e-7 666
15 years 0.01 0.97 [0.60, 1.58] 9.1e-1 142
5 years 0.00 3.64 [2.73, 4.86] 1.9e-18 232
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: J10_INFLUENZA – All influenza
GWS hits: 0

Survival analyses between endpoints

Plot

before All influenza
after All influenza

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