Hypertensive Renal Disease

I9_HYPTENSRD

nephrosclerosis: Hardening of the walls of the small arteries and arterioles (small arteries that convey blood from arteries to the even smaller capillaries) of the kidney. This condition is caused by hypertension (high blood pressure)

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 I12

Hospital discharge: ICD-9 4039A

Hospital discharge: ICD-8 40399

Cause of death: ICD-10 I12

Cause of death: ICD-9 4039A

Cause of death: ICD-8 40399

801

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

801

Check minimum number of events None

801

Include endpoints None

801

I9_HYPTENSRD

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 I10-I15

Name in latin Morbus hypertensivus renalis

Similar endpoints

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List of similar endpoints to Hypertensive Renal Disease based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	777	260	517
Unadjusted prevalence (%)	0.25	0.15	0.38
Mean age at first event (years)	60.60	58.56	61.62

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	4.25 [2.84, 6.38]	2.5e-12	225
15 years	0.01	1.34 [0.89, 2.03]	1.6e-1	60
5 years	0.00	3.56 [2.36, 5.37]	1.4e-9	65
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_HYPTENSRD – Hypertensive Renal Disease
GWS hits: 0

Survival analyses between endpoints

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Plot

before Hypertensive Renal Disease
after Hypertensive Renal Disease

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Hypertensive Renal Disease

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