Secondary hypertension

I9_HYPTENSEC

secondary hypertension: High blood pressure caused by an underlying medical condition.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 I15
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 I15
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

2123

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2123

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Check minimum number of events None

2123

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Include endpoints None

2123

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I9_HYPTENSEC

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I10-I15
Name in latin Hypertensio secundaria

Summary Statistics

Key figures

All Female Male
Number of individuals 2045 878 1167
Unadjusted prevalence (%) 0.66 0.51 0.86
Mean age at first event (years) 54.13 52.97 55.00

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 6.87 [5.08, 9.31] 1.2e-35 341
15 years 0.02 3.32 [2.57, 4.30] 7.7e-20 144
5 years 0.01 6.53 [4.99, 8.55] 1.6e-42 124
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_HYPTENSEC – Secondary hypertension
GWS hits: 0

Survival analyses between endpoints

Plot

before Secondary hypertension
after Secondary hypertension

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Drugs most likely to be purchased after Secondary hypertension