Cerebral atherosclerosis


cerebral atherosclerosis: Vascular diseases characterized by thickening and hardening of the walls of ARTERIES inside the SKULL. There are three subtypes: (1) atherosclerosis with fatty deposits in the ARTERIAL INTIMA; (2) Monckeberg's sclerosis with calcium deposits in the media and (3) arteriolosclerosis involving the small caliber arteries. Clinical signs include HEADACHE; CONFUSION; transient blindness (AMAUROSIS FUGAX); speech impairment; and HEMIPARESIS.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 I67.2
Hospital discharge: ICD-9 4370
Hospital discharge: ICD-8 437
Cause of death: ICD-10 I67.2
Cause of death: ICD-9 4370
Cause of death: ICD-8 437


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9


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Check minimum number of events None


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Include endpoints None


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Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 I67
Name in latin Atherosclerosis cerebralis

Summary Statistics

Key figures

All Female Male
Number of individuals 221 82 139
Unadjusted prevalence (%) 0.07 0.05 0.10
Mean age at first event (years) 70.25 70.82 69.92


Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: I9_CEREBATHER – Cerebral atherosclerosis
GWS hits: 0

Survival analyses between endpoints


before Cerebral atherosclerosis
after Cerebral atherosclerosis

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Drugs most likely to be purchased after Cerebral atherosclerosis