Diseases of middle ear and mastoid

H8_MIDDLEMASTOID

suppurative otitis media: Inflammation of the middle ear with purulent discharge.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 H65-H75
Cause of death: ICD-10 H65-H75

12593

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

12593

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Check minimum number of events None

12593

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H8_MIDDLEMASTOID

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Diseases of middle ear and mastoid based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

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Summary Statistics

Key figures

All Female Male
Number of individuals 19403 11089 8314
Unadjusted prevalence (%) 6.29 6.39 6.16
Mean age at first event (years) 23.53 22.60 24.77

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.57 [1.28, 1.93] 2.0e-5 848
15 years 0.01 1.07 [0.88, 1.31] 5.0e-1 405
5 years 0.00 1.52 [1.23, 1.88] 1.3e-4 163
1 year 0.00 2.87 [2.11, 3.90] 1.8e-11 57

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H8_MIDDLEMASTOID – Diseases of middle ear and mastoid
GWS hits: 4

Survival analyses between endpoints

Plot

before Diseases of middle ear and mastoid
after Diseases of middle ear and mastoid

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Drugs most likely to be purchased after Diseases of middle ear and mastoid